The cancer smart bomb is a nano drug delivery system under development by Dr. Fahmy and colleagues at Yale University. They are developing a new cancer treatment that simultaneously attacks cancer cells and boosts the patient’s immune system. The treatment, which has successfully been tested on mice, uses small hollow spheres, called nanolipogels to deliver the two-prong attack. Some nanolipogels become stuck in leaky tumor blood vessels, where they rally the body’s own immune defenses by releasing interleukin-2 (green). Nanolipogels continuing into the tumor unleash an anti-cancer drug to attack the tumor cells. Winner of AOI 2013 Research and Communication Category (professional).